Department of Experimental Medicine

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  1. 2017
  2. Published

    Hyperpolarized 13C-MRSI and PET (hyperPET) in an Osteomyelitis Pig Model: A Pilot Study

    Rahbek, S., Gutte, H., Johannesen, H. H., Koch, J., Jensen, Louise Kruse, Dich-Jørgensen, K., Jensen, Henrik Elvang, Hansen, A. E. & Kjær, A., Mar 2017, In: IEEE Transactions on Radiation and Plasma Medical Sciences. 1, 2, 4 p., 164-167.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate

    Wahlestedt, M., Erlandsson, E., Kristiansen, T., Lu, R., Brakebusch, Cord Herbert, Weissman, I. L., Yuan, J., Martin Gonzalez, Javier & Bryder, D., 22 Feb 2017, In: Nature Communications. 8, 8 p., 14533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development

    Sankar, A., Kooistra, S. M., Martin Gonzalez, Javier, Ohlsson, C., Poutanen, M. & Helin, K., 1 Jan 2017, In: Development (Cambridge). 144, 18, p. 3264-3277 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Early implant-associated osteomyelitis results in a peri-implanted bacterial reservoir

    Jensen, Louise Kruse, Koch, J., Aalbæk, Bent, Moodley, Arshnee, Bjarnsholt, Thomas, Kragh, K. N., Petersen, A. & Jensen, Henrik Elvang, Jan 2017, In: APMIS - Journal of Pathology, Microbiology and Immunology. 125, 1, p. 38-45 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Active and Passive Immunization Against Staphylococcus aureus Periprosthetic Osteomyelitis in Rats

    Søe, Niels Henrik, Jensen, N. V., Jensen, Asger Lundorff, Koch, J., Poulsen, Steen Seier, Pier, G. B. & Johansen, Helle Krogh, 2017, In: In Vivo. 31, 1, p. 45-50 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Anæstesi, Analgesi og Eutanasi

    Abelson, Klas, 2017, Forsøgsdyrkundskab: En håndbog om forsøgsdyr og dyreforsøg. Bratbo Sørensen, D. (ed.). Denmark: Københavns Universitet, p. 69-96

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review

  8. Published

    Buprenorphine alleviation of pain does not compromise the rat monoarthritic pain model

    Berke, M. S. & Abelson, Klas, 2017, In: Scandinavian Journal of Pain. 16, p. 167-167 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  9. Published

    Choice of rat strain in pre-clinical pain-research–Does it make a difference for translation from animal model to human condition?

    Hestehave, Sara, Munro, G., Brønnum Pedersen, T. & Abelson, Klas, 2017, In: Scandinavian Journal of Pain. 16, p. 187-187 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  10. Published

    Few long-term consequences after prolonged maternal separation in female Wistar rats

    Lundberg, S., Abelson, Klas, Nylander, I. & Roman, E., 2017, In: PloS one. 12, 12, p. 1-22 e0190042.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Håndtering, hold og brug af forsøgsdyr

    Abelson, Klas, Krohn, T. C. & Østergaard, Grete, 2017, Forsøgsdyrkundskab: En håndbog om forsøgsdyr og dyreforsøg. Bratbo Sørensen, D. (ed.). Denmark: Københavns Universitet, p. 37-68

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review

  12. Published

    Novel porcine model of implant-associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response

    Jensen, Louise Kruse, Koch, J., Dich-Jørgensen, K., Aalbæk, Bent, Petersen, A., Fuursted, K., Bjarnsholt, Thomas, Kragh, K. N., Tøtterup, M., Bue, M., Hanberg, P., Søballe, K., Heegaard, P. M. H. & Jensen, Henrik Elvang, 2017, In: Journal of Orthopaedic Research. 35, 10, p. 2211–2221

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2016
  14. Published

    Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings

    Madsen, M. F., Kanters, Jørgen K., Pedersen, P. J., Haugaard, M. M., Carstensen, Helena, Olsen, Lisbeth Høier & Buhl, Rikke, 28 Nov 2016, In: BMC Veterinary Research. 12, 10 p., 266.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Carotid Catheterization and Automated Blood Sampling Induce Systemic IL-6 Secretion and Local Tissue Damage and Inflammation in the Heart, Kidneys, Liver and Salivary Glands in NMRI Mice

    Teilmann, A. C., Rozell, B., Kalliokoski, Otto, Hau, Jann & Abelson, Klas, 10 Nov 2016, In: P L o S One. 11, 11, p. 1-14 14 p., e0166353.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Fighting for the family: overcoming distances in time and space

    Heiselberg, M. H., 8 Nov 2016, In: Critical Military Studies. 3, 1, p. 69-86 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    SCAI promotes DNA double-strand break repair in distinct chromosomal contexts

    Hansen, R. K., Mund, A., Poulsen, S. L., Sandoval, M., Klement, K., Tsouroula, K., Tollenaere, M. A. X., Räschle, M., Soria, R., Offermanns, S., Worzfeld, T., Grosse, R., Brandt, D. T., Rozell, B., Mann, M., Cole, F., Soutoglou, E., Goodarzi, A. A., Daniel, J. A., Mailand, N. & 1 others, Bekker-Jensen, Simon Holst, 7 Nov 2016, In: Nature Cell Biology. 18, 12, p. 1357–1366

    Research output: Contribution to journal › Letter › Research › peer-review

  18. Published

    Applicability of Commercially Available ELISA Kits for the Quantification of Faecal Immunoreactive Corticosterone Metabolites in Mice

    Abelson, Klas, Kalliokoski, Otto, Teilmann, A. C. & Hau, Jann, 1 Nov 2016, In: In Vivo. 30, 6, p. 739-744 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Comparison of Per Diem Rates in Europe and the USA

    Hau, Jann & Kalliokoski, Otto, Sep 2016, In: American Association for Laboratory Animal Science. Journal. 55, 5, p. 679-680 2 p., PS1.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  20. Published

    The Effect of Induced Antibodies with Respect to Neutralization, Clearance Rate and Functional Activity in a Rabbit/Infliximab Model

    Henriksen, M. L., Teisner, A., Kjeldsen, J., Kalliokoski, Otto, Hau, Jann & Hansen, S. W. K., Sep 2016, In: In Vivo. 30, 5, p. 557-565 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency

    Martin Gonzalez, Javier, Morgani, S. M., Bone, Robert Alexander, Bonderup, K., Abelechian, Sahar, Brakebusch, Cord Herbert & Brickman, Joshua Mark, 9 Aug 2016, In: Stem Cell Reports. 7, 2, p. 177-91 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Angiogenesis PET Tracer Uptake (68Ga-NODAGA-E[(cRGDyK)]₂) in Induced Myocardial Infarction in Minipigs

    Rasmussen, T., Follin, Bjarke, Kastrup, J., Brandt-Larsen, M., Madsen, J., Emil Christensen, T., Hammelev, Karsten Pharao, Hasbak, P. & Kjær, Andreas, 17 Jun 2016, In: Diagnostics. 6, 2, 4 p., 26.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Myocardial perfusion of infarcted and normal myocardium in propofol-anesthetized minipigs using 82Rubidium PET

    Rasmussen, T., Follin, Bjarke, Kastrup, J., Christensen, T. E., Hammelev, Karsten Pharao, Kjær, Andreas & Hasbak, P., Jun 2016, In: Journal of Nuclear Cardiology. 23, 3, p. 599-603 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Welfare indicators in laying hens in relation to nest exclusion

    Alm, M., Tauson, R., Holm, L., Wichman, A., Kalliokoski, Otto & Wall, H., Jun 2016, In: Poultry Science. 95, 6, p. 1238-1247 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Protective Effect of Chronic Schistosomiasis in Baboons Coinfected with Schistosoma mansoni and Plasmodium knowlesi

    Nyakundi, R. K., Nyamongo, O., Maamun, J., Akinyi, M., Mulei, I., Farah, I. O., Blankenship, D., Grimberg, B., Hau, Jann, Malhotra, I., Ozwara, H., King, C. L. & Kariuki, T. M., May 2016, In: Infection and Immunity. 84, 5, p. 1320-30 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Effects of Implant-Associated Osteomyelitis on Cefuroxime Bone Pharmacokinetics: Assessment in a Porcine Model

    Tøttrup, M., Bue, M., Koch, J., Jensen, Louise Kruse, Hanberg, P., Aalbæk, Bent, Fuursted, K., Jensen, Henrik Elvang & Søballe, K., 2 Mar 2016, In: Journal of Bone and Joint Surgery: American Volume. 98, 5, p. 363-369 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Robust retention and transfer of tool construction techniques in chimpanzees (Pan troglodytes)

    Vale, G. L., Flynn, E. G., Pender, L., Price, E., Whiten, A., Lambeth, S. P., Schapiro, S. & Kendal, R. L., 1 Feb 2016, In: Journal of Comparative Psychology. 130, 1, p. 24-35 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber)

    Jørgensen, K. B., Krogh-Jensen, K., Pickering, Darryl S, Kanui, T. & Abelson, Klas, 1 Jan 2016, In: Journal of Comparative Physiology A. Sensory, neural, and behavioral physiology. 202, 1, p. 7-15 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Albumin Is an Overlooked but Highly Relevant Allergen Potentially Affecting Laboratory Animal Professionals

    Kalliokoski, Otto, Kousted, T. M., Koch, J. & Hau, Jann, 2016, In: American Association for Laboratory Animal Science. Journal. 55, 5, p. 696 1 p., PS70.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  30. Published

    Implementation of a functional observation battery for the assessment of postoperative well-being in rats subjected to fimbria-fornix transections

    Marschner, L., Wogensen, E., Mogensen, J. & Abelson, Klas, 2016, In: In Vivo. 30, 2, p. 77-82

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified?

    Olsen, H. G., Kjeldgaard-Hansen, M., Tveden-Nyborg, Pernille, Birck, M. M., Hammelev, Karsten Pharao, Vegge, A., Aalbæk, Bent, Leifsson, Páll S., Jensen, Henrik Elvang, Iburg, T., Heegaard, P. M. H. & Nielsen, O. L., 2016, In: BMC Research Notes. 9, p. 1-10 10 p., 99.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2015
  33. Published

    Contribution of Lipocalin-2 from Both Myeloid Cells and Epithelium/Liver Is Required for Optimal Resistance to K. Pneumonia Infection

    Cramer, E. P., Dahl, S. L., Rozell, B., Knudsen, K. J., Thomsen, K., Moser, Claus Ernst, Borregaard, N. & Cowland, J. B., 3 Dec 2015, In: Blood. 126, 23, p. 883-883 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  34. Published

    Neuroanatomical correlates of personality in chimpanzees (Pan troglodytes): Associations between personality and frontal cortex

    Latzman, R. D., Hecht, L. K., Freeman, H. D., Schapiro, S. & Hopkins, W. D., Dec 2015, In: NeuroImage. 123, p. 63-71

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    ESTABLISHING A BEHAVIORAL MANAGEMENT PROGRAM FOR GERIATRIC CHIMPANZEES

    Bridges, J. P., Haller, R. L., Buchl, S. J., Magden, E. R., Lambeth, S. P. & Schapiro, S. J., Nov 2015, In: American Journal of Primatology. 77, S1, p. 111-111 177.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  36. Published

    Suppressor of Fused Plays an Important Role in Regulating Mesodermal Differentiation of Murine Embryonic Stem Cells In Vivo

    Hoelzl, M. A., Heby-Henricson, K., Bilousova, G., Rozell, B., Kuiper, R. V., Kasper, M., Toftgard, R. & Teglund, S., 21 Oct 2015, In: Stem Cells and Development. 24, 21, p. 2547-2560

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Transgene silencing of the Hutchinson-Gilford progeria syndrome mutation results in a reversible bone phenotype, whereas resveratrol treatment does not show overall beneficial effects

    Strandgren, C., Nasser, H. A., McKenna, T., Koskela, A., Tuukkanen, J., Ohlsson, C., Rozell, B. & Eriksson, M., Aug 2015, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29, 8, p. 3193-3205 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses

    Haugaard, M. M., Hesselkilde, E. Z., Pehrson, S. M., Carstensen, Helena, Madsen, M. F., Præstegaard, K. F., Sørensen, U. S., Diness, J. G., Grunnet, M., Buhl, Rikke & Jespersen, Thomas, Apr 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 4, p. 825-835 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior

    Baek, J., Schmidt, E., Viceconte, N., Strandgren, C., Pernold, K., Richard, T. J. C., Van Leeuwen, F. W., Dantuma, N. P., Damberg, P., Hultenby, K., Ulfhake, B., Mugnaini, E., Rozell, B. & Eriksson, M., 1 Mar 2015, In: Human Molecular Genetics. 24, 5, p. 1305-1321 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The importance of witnessed agency in chimpanzee social learning of tool use

    Hopper, L. M., Lambeth, S. P., Schapiro, S. & Whiten, A., Mar 2015, In: Behavioural Processes. 112, p. 120-129

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Genetic basis in motor skill and hand preference for tool use in chimpanzees (Pan troglodytes)

    Hopkins, W. D., Reamer, L., Mareno, M. C. & Schapiro, S., 7 Feb 2015, In: Proceedings of the Royal Society B: Biological Sciences. 282, 1800, p. 1-7 20141223.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Dynamic regulation of cerebral DNA repair genes by psychological stress

    Forsberg, K., Aalling, Nadia, Wörtwein, Gitta, Loft, Steffen, Møller, Peter, Hau, Jann, Hageman, I., Jørgensen, M. B. & Jørgensen, Anders, 15 Jan 2015, In: Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 778, p. 37-43 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The distorting effect of varying diets on fecal glucocorticoid measurements as indicators of stress: A cautionary demonstration using laboratory mice

    Kalliokoski, Otto, Teilmann, A. C., Abelson, Klas & Hau, Jann, 15 Jan 2015, In: General and Comparative Endocrinology. 211, p. 147-153 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Selective and contagious prosocial resource donation in capuchin monkeys, chimpanzees and humans

    Claidiere, N., Whiten, A., Mareno, M. C., Messer, E. J. E., Brosnan, S. F., Hopper, L. M., Lambeth, S. P., Schapiro, S. & McGuigan, N., 6 Jan 2015, In: Scientific Reports. 5, p. 1-11 7631.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Chimpanzees copy dominant and knowledgeable individuals: implications for cultural diversity

    Kendal, R., Hopper, L. M., Whiten, A., Brosnan, S. F., Lambeth, S. P., Schapiro, S. & Hoppitt, W., Jan 2015, In: Evolution and Human Behavior. 36, 1, p. 65-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The applicability of a gel delivery system for self-administration of buprenorphine to laboratory mice

    Hovard, A. M. B., Teilmann, A. C., Hau, Jann & Abelson, Klas, Jan 2015, In: Laboratory Animals. 49, 1, p. 40-45 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses

    Haugaard, M. M., Pehrson, S., Carstensen, Helena, Madsen, M. F., Hesselkilde, E. Z., Præstegaard, K. F., Diness, J. G., Grunnet, M., Jespersen, Thomas & Buhl, Rikke, 2015, In: Journal of Veterinary Internal Medicine. 29, 1, p. 339-347 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Influence of intense neuromuscular blockade on surgical conditions during laparotomy: a pig model

    Madsen, M. V., Donatsky, A. M., Jensen, B. R., Rosenberg, Jacob, Hammelev, Karsten Pharao & Gätke, M. R., 2015, In: Journal of Anesthesia. 29, 1, p. 15-20 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Specific antibodies to Staphylococcus aureus  biofilm are present in serum from pigs with osteomyelitis

    Jensen, Louise Kruse, Jensen, Henrik Elvang, Koch, J., Bjarnsholt, Thomas, Eickhardt-Dalbøge, S. R. & Shirtliff, M., 2015, In: In Vivo. 29, p. 555-560 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. 2014
  51. Published

    The Lonely Mouse - Single Housing Affects Serotonergic Signaling Integrity Measured by 8-OH-DPAT-Induced Hypothermia in Male Mice

    Kalliokoski, Otto, Teilmann, A. C., Jacobsen, K. R., Abelson, Klas & Hau, Jann, 1 Dec 2014, In: P L o S One. 9, 12, p. 1-13 13 p., e111065.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Physiological and Pathological Impact of Blood Sampling by Retro-Bulbar Sinus Puncture and Facial Vein Phlebotomy in Laboratory Mice

    Teilmann, A. C., Nygaard Madsen, A., Holst, Birgitte, Hau, Jann, Rozell, B. & Abelson, Klas, 26 Nov 2014, In: PloS one. 9, 11, p. 1-19 19 p., e113225.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Age-related effects in the neocortical organization of chimpanzees: Gray and white matter volume, cortical thickness, and gyrification

    Autrey, M. M., Reamer, L. A., Mareno, M. C., Sherwood, C. C., Herndon, J. G., Preuss, T., Schapiro, S. J. & Hopkins, W. D., 1 Nov 2014, In: NeuroImage. 101, p. 59-67 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Amyloid beta1–42 and the phoshorylated tau threonine 231 in brains of aged cynomolgus monkeys (Macaca fascicularis)

    Darusman, H. S., Gjedde, Albert, Sajuthi, D., Schapiro, S., Kalliokoski, Otto, Kristianingrum, Y. P., Handaryani, E. & Hau, Jann, Nov 2014, In: Frontiers in Aging Neuroscience. 6, p. 1-7 7 p., 313.

    Research output: Contribution to journal › Journal article › Research › peer-review

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